Structures Solved and deposited at Protein Data Bank (PDB)

25. Ashli Morgan, Krishna Mohan Sepuru, Wei Feng, Krishna Rajarathnam and Xu

      Wang. Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding 

      Protein A.  Biochemistry, 2015, 54 (32), 5113-5119.

24. Prem Raj Joseph, Krishna PM, Krishna Mohan Sepuru and Krishna Rajarathnam. 

      Characterizing Protein–Glycosaminoglycan Interactions Using Solution NMR

      Spectroscopy. Kuberan Balagurunathan et al. (eds.), Glycosaminoglycans:

      Chemistry and Biology. Methods Mol Biol. 2015, 1229, 325-33.

23. G. Sandhya Rani, S. Krishna Mohan and C. Yu.

      Interaction of S100A13 with Receptor for Advanced Glycation End products 

      (RAGE) C2 domain. Biochim Biophys Acta, 2014, 1844(9), 1718-28.

22. Krishna Mohan Sepuru, Krishna PM, Krishna Rajarathnam.

      Solution structure of CXCL5 — A novel chemokine and adipokine implicated in  

      inflammation and obesity. Plos One, 2014, DOI: 10.1371/journal.pone.0093228.

21. S. Krishna Mohan, A. Arun Gupta and C. Yu

      Interaction of S100A6 with Receptor for Advanced Glycation End product (RAGE)  

      V-domain and C2 domain with different affinity. Biochemical and Biophysical

      Research Communications, 2013, 3, 434(2), 328-33.

20. P. Srinivasa Rao, S. Krishna Mohan, and C. Yu

      ¹H, ¹³C and ¹⁵N backbone and side chain resonance assignments of human Halo S100P.  

      Biomol NMR Assign, 2013, 7(1):5-8.

19. Meng-Je Joung, S. Krishna Mohan, and Chin Yu

      Molecular Level Interaction of the Human Synaptotagmin I C2B domain with Inositol   

      Hexaphosphate. Biochemistry, 2012, 51(17): 3675-83.

18. A. Arun Gupta, S. Krishna Mohan, and C. Yu

      ¹H, ¹³C and ¹⁵N backbone and side chain resonance assignments of human halo

      S100A1. Biomol NMR Assign, 2012, 6(2): 213-5.

17. S. Krishna Mohan and C. Yu

      The IL1α-S100A13 hetero-tetrameric complex structure: key component in the  

      non-classical pathway for Interleukin 1 alpha (IL-1α) secretion.  J. Biol. Chem, 2011,

      286, 14608-14617.

16. Hsiao-Wen Huang, S. Krishna Mohan, and C. Yu

      The NMR solution structure of human epidermal growth factor at physiological pH

      Biochemical and Biophysical Research Communications, 2010, 402 (4), 705-710.

15. S. Manoj Kumar, Wang HM, S. Krishna Mohan, Chou RH and C. Yu.

      Molecular level interaction of the human acidic fibroblast growth factor with the  

     antiangiogenic agent, inositol hexaphosphate . Biochemistry, 2010, 49 (50), 10756-10764.

14. S. Krishna Mohan, G. Sandhya Rani, and C. Yu

      The heterohexameric complex structure, a component in the nonclassical pathway

      for fibroblast growth factor1 (FGF1) secretion. J. Biol. Chem (2010) 285 (20), 15464-75.

13. Hsuan-Kuo Chang, S. Krishna Mohan, and C. Yu

      ¹H, ¹³C and ¹⁵N backbone and side chain resonance assignments of human

      interleukin 1a. Biomol NMR Assign, (2010), 4 (1), 59-60.

12. G. Sandhya Rani, S. Krishna Mohan, and C. Yu

      Molecular level interactions of S100A13 with a Amlexanox: Inhibitor for formation

      of the multiprotein complex in the nonclassical pathway of acidic fibroblast growth factor.  

      Biochemistry, 2010, 49(11), 2585-2592.

11. Françoise Bono, Alain Badorc, Frederik De Smet, Pierre Fons, Annelii Ny, Masahiro

      Murakami, Paul Schaeffer, Filip Claes, Marc Tjwa, Frédérique Dol- Isabelle Blanc,

      S Krishna Mohan, Schymkowitz, Simons, Peter Carmeliet, Jean Marc Herbert et.al.

      Discovery of the first small-molecule allosteric inhibitor of a tyrosine kinase receptor:

      Inhibiton of VEGFR2-inhibitor refractory tumors by a multi-FGF receptor modular.

      Belg J Med Oncol , 2010, 4, 83-102.

10. S. Krishna Mohan, G. Sandhya Rani, S. Manoj Kumar and C. Yu

      S100A13-C2A binary complex structure - a key component in the acidic fibroblast growth

     factor for the non-classical pathway. Biochemical and Biophysical Research

     Communications (2009), 380, 514-519. 

9. S. Krishna Mohan and C. Yu

    Structure function relationships of Cobrotoxin from Naja Naja Atra.

    Toxin Rev, 2007, 1-24, 26.

8. S. Krishna Mohan Madhusudhan Raju and P. Ettaiah and P. Rabindra Reddy

    Zinc complexes for hydrolytic cleavage of DNA.

    Ind. J. Chem. 2006 45A, 2381-2391.

7. S. Krishna Mohan, P. Rabindra Reddy and P. Manjula

    A new S4-ligated zinc - peptide 1:2 complex for the hydrolytic cleavage of DNA.  

   Chemistry & Biodiversity, 2006, 3, 657-665.

6. S. Krishna Mohan, P. Rabindra Reddy, and P. Manjula

    Novel peptide based Cu (II) complexes for total hydrolytic cleavage of DNA.

    Chemistry & Biodiversity, 2005), 2 , 1338-1350.

5. S. Krishna Mohan, P. Rabindra Reddy and K. Srinivasa Rao

    Ternary Zinc(II)-Dipeptide Complexes for the Hydrolytic Cleavage of DNA at Physiological    pH. Chemistry & Biodiversity (2005), 2 (5), 672- 683.

4. S. Krishna Mohan, P. Rabindra Reddy and K. Srinivasa Rao

    DNA hydrolytic cleavage by stable Zn(II) dipeptide complexes.

    Ind. J. Chem, 2004, 43A, 2329-2333.

3. K. Srinivasa Rao, S. Krishna Mohan, and P. Rabindra Reddy

    Copper(II) complexes containing N,N donor ligands and dipeptides act as hydrolytic DNA

    cleavage agents. Chemistry & Biodiversity (2004), 1, 839- 853.

2. S. Krishna Mohan, P. Rabindra Reddy, and M. Radhika 

    Stability, Energetics and DNA binding studies of Zinc complexes.

    Ind. J. Chem, 2003, 42A, 2721-2726.

1. S. Krishna Mohan and P. Rabindra Reddy

    Interaction of zinc with cysteinylglycine and histidine containing dipeptides: Relevance to   

    zinc binding sites in transcriptionfactor IIIA. Ind. J. Chem, 2002, 41A, 1816-1820.

INVITED TALKS / ORAL PRESENTATIONS

Ø Krishna Mohan Sepuru. ‘Structural insights into chemokine interactions with glycosaminoglycans and CXCR2 receptor’ at the Community Building Seminar Series in UTMB, Galveston (Mar 2015).

Ø  Krishna Mohan Sepuru ‘Role of glycosaminoglycans in chemokine-mediated in vivo neutrophil trafficking: insight from animal models and structural studies’ INTER-PEG 2015, Bethesda, Washington DC (April 2015)

PAPERS PRESENTED AT SYMPOSIA

1.        Morales E, Sepuru, K. M, Sawant, K, Dhamdhere, M, Rajarathnam, K. Structural and regulatory roles of murine CXCL1 and CXCL2 monomer and dimer.  Summer Undergraduate Research Program, UTMB Galveston TX (Aug 2015).

2.        Sepuru, K. M, Iwahara, J, Rajarathnam, K. Specificity and Diversity of glycosaminoglycan interactions with neutrophil activating chemokines: Insights from solution NMR studies 20^th Annual Sealy Center for Structural biology and Molecular Biophysics Symposium, Galveston TX (May 2015)

3.        Brown, A. J, Sepuru, K. M, Rajarathnam, K. Structural basis of chemokine heterodimers and their glycosaminoglycan-complexes: An NMR approach to characterize system of up to ten species. 20^th Annual Sealy Center for Structural biology and Molecular Biophysics Symposium, Galveston TX (May 2015)

4.        Brown, A. J, Sepuru, K. M, Rajarathnam, K. Structural basis of chemokine heterodimers and their glycosaminoglycan-complexes: An NMR approach to characterize system of up to ten species. 23^rd Texas Protein Folding and Function Meeting, Cleveland, TX (April 2015)

5.        Kirti, S, Poluri K. M, Sepuru, K. M, Troshkina, A, Dutta, A, Rajarathnam, K. Glycosaminoglycan interactions regulate chemokine-mediated in vivo neutrophil trafficking: Insights from animal models. INTER-PEG 2015, Bethesda, Washigton DC (April 2015)

6.        Sepuru, K. M, Iwahara, J, Rajarathnam, K. Specificity and Diversity of glycosaminoglycan interactions with neutrophil activating chemokines: Insights from solution NMR studies. INTER-PEG 2015, Bethesda, Washigton DC (April 2015)

7.        Sepuru, K. M, Rajarathnam, K. Structural characterization of chemokine CXCL5-glycosaminoglycan interactions using solution NMR spectroscopy. Institute for Human Infections and Immunity (IHII) Retreat, Galveston, TX (Dec 2014).

8.        Brown, A. J, Joseph, P. R. B, Sepuru, K. M.; Rajarathnam, K. Characterization of Chemokine Heterodimers and GAG Interactions Using Solution NMR Spectroscopy. 24^th Keck Annual Research Conference, Houston, TX (November 2014)

9.        Sepuru, K. M, Iwahara, J, Rajarathnam, K. Structural characterization of chemokine CXCL5-glycosaminoglycan interactions using solution NMR spectroscopy.  XXVIth International Council on Magnetic Resonance in Biological Systems (ICMRBS) Meeting, Dallas TX (Aug  2014).

10.     Peña, P, Sepuru, K. M, Rajarathnam, K. Finding binding interfaces between CXCL5 monomer and CXCR2 using NMR spectroscopy. Summer Undergraduate Research Program, UTMB Galveston TX (Aug 2014).

11.     Sepuru, K. M, Rajarathnam, K. Structural basis of Chemokine CXCL5-glycosaminoglycan interactions. 19^th Annual Sealy Center for Structural biology and Molecular Biophysics Symposium, Galveston TX (May 2014).

12.     Sepuru, K. M, Iwahara, J, Rajarathnam, K. Structural Basis Chemokine CXCL5 Glycosaminoglycan Interactions. 22nd Texas Protein Folding and Function Meeting, Cleveland, TX (April 2014).

13.     Sepuru, K. M, Rajarathnam, K. Solution structure of CXCR 2 N-domain in complex with interleukin 8. 18^th Annual Sealy Center for Structural biology and Molecular Biophysics Symposium, Galveston TX (May 2013).

14.     S. Krishna Mohan, and Rajarathnam, K. “Solution structure of epithelial-derived neutrophil-activating peptide 78 (ENA-78) and identification of GAG binding sites” 2013 IHII/McLaughlin Colloquium, Galveston, TX, Apr 12, 2013.

15.     S. Krishna Mohan, Mohan,P.M and  Rajarathnam, K. “Solution structure of the CXC type chemokine CXCL5 (ENA-78) and its interactions with glycosaminoglycans” 21st Texas Protein Folding and Function Meeting, Camp Allen, Navasota, TX, Mar 22-24, 2013.

16.     S. Krishna Mohan, G. Sandhya Rani,  Ch. Upendar, S. Manoj Kumar, and C. Yu. Role of S100A13 in the non-classical pathway of FGF-1, The International Society of Magnetic Resonance (ISMAR) -2007, Kenting Taiwan, Sep 14^th to 19^th.

17.     S. Krishna Mohan, G. Sandhya Rani,  Ch. Upendar, S. Manoj Kumar and C. Yu. Role of S100A13 in the non-classical pathway of FGF-1. Asia-Pacific NMR Symposium, 2007, Hsinchu, Taiwan, Sep 12^th to 13^th.

18.     S. Mamoj Kumar, Han-Min Wang, S. Krishna Mohan, Ruey-Hwang Chou, Ping-Chiang Lyu and C. Yu. Molecular level interaction of human acidic fibroblast factor with the antiangiogenic agent, inositol hexaphosphate. 16^th Biophysics Conference, National Dong Hua University, TAIWAN, May 18^th 21^st 2011.

19.     S. Krishna Mohan, and C. Yu. Role of the S100A13 in Non-classical pathway of FGF1. 12^th symposium on recent advances in Biophysics. National Health Research Institute, Zhunan TAIWAN, May 23-25, 2007.

20.     S. Krishna Mohan, and C. Yu. Interaction of S100A13 with p53 peptide 4^th Taiwan-Japan NMR Symposium, 2006.

21.     S. Krishna Mohan, and C. Yu. The NMR study of snake venom proteins-Structure, dynamics, interaction and folding. 11^th Biophysical society meeting, Acadamia Sinica, TAIWAN, 2006

22.     P. Rabindra Reddy and S. Krishna Mohan, P. Manjula. Novel peptide based copper(II) complexes for total hydrolytic cleavage of DNA. 230^th ACS National Meeting, Washington, DC, United States, Aug 28-Sep 1^st, 2005.

23.     P. Rabindra Reddy and S. Krishna Mohan Zinc(II) dipeptide systems for hydrolytic cleavage of DNA. 227^th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004.

24.     P. Rabindra Reddy and S. Krishna Mohan. Influence of side chains of peptides on zinc peptide-DNA interactions. 225^th ACS National Meeting, New Orelans, United States, March, 2003.

25.     S. Krishna Mohan, P. Rabindra Reddy, and M. Radhika. Only zincpeptide complexes recognize DNA as compared to cobalt. Fourth National Symposium in Chemistry, Organized by CRSI, PUNE, Feb 1-3, 2002

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American Chemical Society (ACS)

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Biochemistry

PLosOne

Journal of Biomolecular Structure and Dynamics

The Open Biochemistry Journal

Journal of Glycobiology

Journal of Clinical & Cellular Immunology.

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The journal of Immunotherapy